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Physiogenomix: Genetic Analysis for Training Optimization

Physiogenomix is the genetic component of FitLogic's Training Intelligence Platform. By analyzing your DNA, Physiogenomix provides critical insights that work alongside FitLogic's other enabling technologies—including the FitLogic Intelligence Engine, Age & Gender Normalization, and EnviroNorm—to create truly personalized training prescriptions.

Integration with FitLogic Platform

Your genetic data enhances FitLogic's ability to:

More accurately assess your training response patterns

Optimize training stress calculations based on your genetic recovery rate

Prescribe training intensities aligned with your genetic predispositions

Proactively manage injury risk through genetic insights

Improve performance predictions by accounting for genetic factors

Four Core Genetic Performance Indicators

Physiogenomix analyzes over two dozen genes to assess four critical aspects of athletic performance. Each indicator directly influences how FitLogic's algorithms optimize your training prescription.

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Training Intensity Response

Training Intensity Response is a relative measure of how you respond to high-intensity versus low-intensity training. Based on your genetic variations, you are predisposed to have a greater response to either high or low-intensity training.

Training Impact

Training Intensity Response influences your training emphasis and improvement expectations, specifically related to differences between training above your functional (aerobic) threshold versus at or below it. Proper emphasis and expectations help to ensure that training time and intensities are optimized to achieve improvements that are the most beneficial to overall performance.

 

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Aerobic Potential

Aerobic Potential is a measure of your potential for developing a high aerobic capacity or high oxygen utilization (VO2max). This is not a measure of your current aerobic capacity. Rather, it is a measure of your aerobic trainability--your potential for improvement with proper training.

Training Impact

Aerobic Potential influences how quickly and to what degree you are able to increase your aerobic fitness. This can impact improvement-rate expectations used when optimizing training focus and periodization of training blocks in both short and long training phases.

 

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Recovery Rate

Recovery Rate is a measure of your genetic ability to recover from exercise-induced oxidative stress and inflammation. This includes the level of stress and inflammation produced and the rate at which it is cleared.

Training Impact

Your Recovery Rate primarily influences training intensity and frequency, specifically with regard to higher intensity sessions. It can be used proactively when prescribing training to help ensure planned sessions don't include more training stress than you have time to recovery from prior to your next high-intensity session. Recovery Rate can also impact how much time is required to taper for or recover from a race.

 

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Injury Predisposition

Injury Predisposition is a measure of how genetically prone you are to incurring soft tissue (tendon and ligament) injuries from training.

Training Impact

Your Injury Predisposition primarily influences training intensity and volume, specifically related to high-intensity sessions and rates of increasing volume and long session durations. It can also influence the type warm-up drills and strength training routines that contain high-impact, ballistic movements.

 

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Detailed Genetic Analysis: Your Training-Related SNPs

Physiogenomix goes beyond simple genetic categories to provide detailed analysis of specific Single Nucleotide Polymorphisms (SNPs) that directly impact your athletic performance.

FitLogic marries two decades of training data with breakthrough genetic research to create the world's most definitive genetic profile for athletes. Your results include a detailed breakdown of specific genes that relate directly to physical training. By uploading your genome, your training is further optimized based on your genetics to improve its efficacy delivering even better results for you.

 

Some of the Key Performance Genes We Analyze

ACE (Angiotensin Converting Enzyme)

Influences endurance capacity, muscle fiber composition, and training response.

ACTN3 (Alpha Actinin 3)

The "speed gene" affecting fast-twitch muscle fiber development.

ADRB2 (Beta-2 Adrenergic Receptor)

Impacts fat metabolism, endurance efficiency, and VO2max improvements.

AGT (Angiotensinogen)

Affects blood pressure response and cardiovascular adaptation.

BDKRB2 (Bradykinin Receptor B2)

Influences muscle efficiency and endurance performance.

COL1A1 & COL5A1 (Collagen Types)

Determine tendon and ligament strength and injury susceptibility.

CRP (C-Reactive Protein)

Associated with inflammation response and recovery speed.

GDF5 (Growth Differentiation Factor 5)

Affects bone and joint development and injury risk.

GSTM1 (Glutathione S-Transferase M1)

Important for antioxidant production and recovery from oxidative stress.

IL6 (Interleukin 6)

Regulates inflammatory response and muscle repair.

IL6R (Interleukin 6 Receptor)

Works with IL6 to modulate inflammation and recovery.

NRF2 (Nuclear Factor Erythroid 2)

Master regulator of antioxidant response to exercise stress.

PPARA (PPAR Alpha)

Regulates fat metabolism and endurance capacity.

PPARGC1A (PGC-1α)

Key regulator of mitochondrial biogenesis and aerobic capacity.

SOD2 (Superoxide Dismutase 2)

Critical antioxidant enzyme influencing recovery.

TNF (Tumor Necrosis Factor)

Pro-inflammatory cytokine affecting muscle recovery.

TRHR (Thyrotropin-Releasing Hormone Receptor)

Influences metabolic rate and training adaptation.

VDR (Vitamin D Receptor)

Affects muscle strength, bone health, and immune function.

VEGFA (Vascular Endothelial Growth Factor A)

Promotes blood vessel formation and oxygen delivery to muscles.

Comprehensive Analysis Approach

Physiogenomix evaluates each genetic marker not in isolation, but as part of your complete athletic profile. This systems-based approach considers:

Gene-gene interactions

How your genetic variants work together to influence performance

Training responsiveness

Your likely adaptation to different training stimuli based on genetic factors

Recovery patterns

Optimal rest and recovery strategies matched to your genetics

Injury risk factors

Proactive measures to prevent common athletic injuries

Performance optimization

Training load and intensities matched to your genetic profile

How Physiogenomix Works

Upload Your DNA Data

Compatible with 23andMe, Ancestry, and most raw genome formats. The upload process takes less than 30 seconds.

Receive Your Athletic Profile

Within minutes, you'll receive your comprehensive genetic athletic analysis including all four performance categories and detailed SNP breakdown.

Automatic Integration with FitLogic

Your genetic insights automatically enhance FitLogic's AI algorithms, improving the accuracy of your training prescriptions, recovery recommendations, and performance predictions.

Frequently Asked Questions

Do I need to take a new DNA test?

No. If you've already done 23andMe, Ancestry, or similar testing, simply upload your existing data.

How does Physiogenomix improve my FitLogic training?

Your genetic data helps FitLogic's AI better understand your individual training response patterns, recovery needs, and injury risks, allowing for more personalized and effective training prescriptions.

Is FitLogic still effective without genetic data?

Yes. FitLogic's AI is highly effective even without genetic data. However, adding your genetic profile provides an additional layer of personalization and helps the system make more informed decisions about your training.

Is my genetic data secure?

Yes. We use encryption and never share your data without explicit consent.

Physiogenomix is an enabling technology within the FitLogic Training Intelligence Platform, working alongside the FitLogic Intelligence Engine, Age & Gender Normalization, EnviroNorm, and other components to deliver comprehensive training optimization.

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What This Means for You

The comprehensiveness and contextualization of the FitLogic Dataset translates directly into tangible benefits for every athlete:

More Accurate Predictions

When your training decisions are based on millions of properly contextualized data points, predictions become remarkably accurate. You'll know what fitness gains to expect, what race times are achievable, and how different training approaches will impact your performance.

Truly Personalized Training

Your training isn't based on generic templates or one-size-fits-all philosophies. It's built on deep understanding of how athletes with your genetics, your fitness level, your constraints, and your goals actually respond to training.

Faster Adaptation

The system learns and adapts quickly to changes in your fitness, schedule, or environment because it has seen similar patterns thousands of times before. When life happens, your training adjusts intelligently, not generically.

Fewer Injuries

By understanding individual stress tolerance, recovery patterns, and genetic predispositions across a vast population, the system can push you appropriately hard while respecting your body's limits—limits that would be invisible without this comprehensive data.

Confident Decision Making

When FitLogic decides whether you should push through fatigue or take a rest day, chooses between training options, or plans your race strategy, you can have complete confidence in those decisions. They're based on the most complete training intelligence available anywhere—not guesswork, not generic templates, but deep understanding derived from comprehensive, contextualized data.